Table 3.
The counts of WBC, Cytokines and lymphocytes in positive and negative groups by mNGS
| Positive | Negative | P | |
|---|---|---|---|
| Cytokines pg/ml | |||
| IL-2 | 100.35 + 68.21 | 1.31 + 0.94 | 0.511 |
| IL-4 | 2.74 + 0.41 | 1.52 + 0.94 | 0.206 |
| IL-6 | 70.8 + 18.27 | 68.96 + 33.18 | 0.964 |
| TNF-α | 2.48 + 0.42 | 2.26 + 1.32 | 0.842 |
| IL-17a | 13.77 + 2.35 | 10.45 + 8.01 | 0.592 |
| IL-8 | 1154 + 0 | – | – |
| IL-10 | 26.14 + 7.75 | 8.29 + 3.33 | 0.044 |
| IFN-γ | 8.91 + 1.89 | 13.59 + 6.92 | 0.361 |
| Cellular Immunity % | |||
| CD4/CD8 | 1.42 + 0.23 | 2.06 + 0.44 | 0.185 |
| Th cell | 35 + 3.36 | 43.83 + 5.75 | 0.201 |
| Ts cell | 68.06 + 3.07 | 66.67 + 3.64 | 0.18 |
| NK cell | 15.71 + 2.17 | 15.5 + 1.89 | 0.958 |
| B cell | 13.53 + 2.94 | 12.83 + 3.73 | 0.899 |
| T cell | 68.06 + 3.07 | 66.67 + 3.64 | 0.958 |
| WBC ×109 | 8.32 + 0.52 | 7.36 + 0.48 | 0.283 |
| Neu× 109 | 6.99 + 0.58 | 5.38 + 0.48 | 0.109 |
| PCT ng/ml | 0.34 + 0.17 | 3.42 + 3.32 | 0.112 |
| CRP mg/l | 87.63 + 8.32 | 63.61 + 13.47 | 0.129 |
Abbreviations: mNGS metagenomic next-generation sequencing, WBC white blood cells, IL- interleukin-, IFN-γ Interferon-γ, TNF-α Tumor Necrosis Factor-α, CD4 Cluster of Differentiation 4 receptors, CD8 Cluster of Differentiation 8 receptors, Th helper T cell, Ts suppressor T cell, NK natural killer cell, Neu neutrophil, PCT procalcitonin, CRP C-reactive protein