Table 2.
Age and cardiovascular risk factors in relation to quartiles of log ALT in men (mean and SD or numbers and %)
| Variables | Log ALT quartiles | P (trend) | |||
|---|---|---|---|---|---|
| Log ALT (U/L) | < 1.32 | 1.32 – 1.44 | 1.45 – 1.58 | ≥ 1.58 | |
| N | 631 | 662 | 622 | 637 | |
| Age (years) | 64.1 (12.4) | 61.1 (12.3) | 59.6 (11.5) | 56.5 (11.6) | < 0.001 |
| BMI (kg/m2) | 25.3 (3.3) | 26.6 (3.2) | 27.9 (3.5) | 29.1 (5.0) | < 0.001 |
| Waist-to-hip-ratio | 0.93 (0.07) | 0.95 (0.06) | 0.95 (0.06) | 0.98 (0.06) | < 0.001 |
| Systolic blood pressure (mmHg) | 140.0 (22.0) | 140.1 (20.7) | 141.7 (20.8) | 140.8 (20.5) | 0.50 |
| Diastolic blood pressure (mmHg) | 79.2 (10.0) | 81.1 (10.1) | 82.4 (10.0) | 84.0 (10.6) | < 0.001 |
| Total/HDL cholesterol ratio | 3.88 (1.24) | 4.15 (1.31) | 4.35 (1.32) | 4.73 (1.43) | < 0.001 |
| Triglycerides (mmol/L) | 1.39 (0.75) | 1.55 (0.99) | 1.72 (0.96) | 1.97 (1.16) | < 0.001 |
| Log hs-CRP (mg/dl) | 0.16 (0.48) | 0.13 (0.42) | 0.15 (0.39) | 0.22 (0.40) | 0.10 |
| Log s-glucose (mmol/L) | 0.71 (0.07) | 0.72 (0.07) | 0.73 (0.07) | 0.74 (0.09) | < 0.001 |
| Log HbA1C (%) | 0.76 (0.05) | 0.76 (0.04) | 0.76 (0.04) | 0.77 (0.05) | 0.007 |
| Heavy exerciser† | 98 (15.5) | 131 (19.8) | 104 (16.7) | 98 (15.4) | 0.64 |
| Alcohol 2–3 times per week | 134 (21.2) | 159 (24.0) | 146 (23.5) | 156 (24.5) | 0.24 |
ALT alanine aminotransferase, BMI body mass index, HbA1C glycated haemoglobin, HDL high density lipoprotein, Hs-CRP high-sensitive C-reactive protein, SD standard deviation
†Moderate or hard leisure exercise ≥ 2 h per week