Table 3.
Age and cardiovascular risk factors in relation to quartiles of log ALT in women (mean and SD or numbers and %)
| Variables | Log ALT quartiles | P (trend) | |||
|---|---|---|---|---|---|
| Log ALT (U/L) | < 1.23 | 1.23 – 1.34 | 1.35–1.46 | > 1.46 | |
| N | 717 | 745 | 684 | 712 | |
| Age (years) | 56.3 (15.0) | 60.8 (12.7) | 61.9 (11.6) | 60.9 (10.8) | < 0.001 |
| BMI (kg/m2) | 25.2 (3.8) | 26.1 (4.3) | 27.0 (4.6) | 28.4 (4.9) | < 0.001 |
| Waist-to-hip-ratio | 0.86 (0.07) | 0.86 (0.07) | 0.87 (0.06) | 0.89 (0.07) | < 0.001 |
| Systolic blood pressure (mmHg) | 132.1 (26.0) | 138.3 (25.8) | 139.7 (25.0) | 144.9 (25.9) | < 0.001 |
| Diastolic blood pressure (mmHg) | 74.3 (10.6) | 75.5 (10.2) | 76.1 (10.0) | 78.8 (11.1) | < 0.001 |
| Total/HDL cholesterol ratio | 3.51 (1.06) | 3.59 (1.00) | 3.70 (1.16) | 4.17 (1.28) | < 0.001 |
| Triglycerides (mmol/L) | 1.27 (0.65) | 1.31 (0.66) | 1.43 (0.78) | 1.70 (1.00) | < 0.001 |
| Log hs-CRP (mg/dl) | 0.13 (0.49) | 0.10 (0.44) | 0.14 (0.43) | 0.24 (0.41) | < 0.001 |
| Log s-glucose (mmol/L) | 0.69 (0.07) | 0.70 (0.06) | 0.71 (0.06) | 0.72 (0.08) | < 0.001 |
| Log HbA1C (%) | 0.74 (0.04) | 0.75 (0.04) | 0.75 (0.04) | 0.76 (0.05) | < 0.001 |
| Heavy exerciser† | 94 (13.1) | 126 (16.9) | 113 (16.5) | 43 (6.0) | 0.85 |
| Alcohol ≥ 2–3 times per week | 122 (17.0) | 139 (18.7) | 120 (17.5) | 127 (17.8) | 0.88 |
ALT alanine aminotransferase, BMI body mass index, HbA1C glycated haemoglobin, HDL high density lipoprotein, Hs-CRP high-sensitive C-reactive protein, SD standard deviation
†Moderate or hard leisure exercise ≥ 2 h per week