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Covert |
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Abnormal tests without clinical manifestations. |
Minimal |
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Alterations in psychometric or neuropsychological tests exploring attention, working memory, psychomotor speed, visuospatial ability and executive functions. No clinical neurological signs. |
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Grade I |
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Euphoria or anxiety, shortened attention span, impairment of addition or subtraction, altered sleep rhythm and lack of awareness. |
Cognitive/behavioral decay with respect to his/her standard on clinical examination or to the caregivers. |
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Overt |
Lethargy or apathy, disorientation for time, |
Disorientation for time (at least three of the following |
Grade II |
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obvious personality changes, inappropriate behavior, dyspraxia, asterixis. |
are wrong: day of the month, day of the week, month and season or year) ± the other mentioned symptoms. |
Grade III |
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Somnolence to semi-stupor but response to stimuli, confusion, gross disorientation, bizarre behavior. |
Disorientation also for space (at least three of the following are wrong: country, state or region, city or place) ± the other mentioned symptoms. |
Grade IV |
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Coma |
Lacking response to painful stimuli. |