Table 3.
Data relating to effectiveness and cost-effectiveness of applying metabolic GA estimation algorithm to different BW cohorts
| BW range | Infants tested | Preterm births based on ultrasound (37-wk cutoff), n | Preterm births identified by basic algorithm (<38 wk), n | Number of preterm births identified by metabolic GA algorithm (<38 wk), n | Total cost excluding setup | Total cost including setup | Incremental cost per preterm infant identified vs basic algorithm (excluding setup) | Incremental cost per preterm infant identified vs basic algorithm (including setup) |
|---|---|---|---|---|---|---|---|---|
| 2500–2600 g | 117 | 14.0 | 5.3 | 9.3 | $41,911 | $62,376 | $10,478 | $15,594 |
| 2500–2700 g | 219 | 16.0 | 5.3 | 10.0 | $46,810 | $67,276 | $10,031 | $14,416 |
| 2500–2800 g | 364 | 29.3 | 5.3 | 14.7 | $53,803 | $74,268 | $5765 | $7957 |
| 2500–2900 g | 493 | 33.3 | 5.3 | 16.0 | $60,000 | $80,465 | $5625 | $7544 |
| 2500–3000 g | 689 | 37.3 | 5.3 | 16.0 | $69,464 | $89,929 | $6512 | $8431 |
| 2500–3100 g | 777 | 37.3 | 5.3 | 16.0 | $73,693 | $94,158 | $6909 | $8827 |
| 2500–3200 g | 871 | 38.7 | 5.3 | 17.3 | $78,215 | $98,680 | $6901 | $8707 |
| 2500–3300 g | 951 | 40.0 | 5.3 | 17.3 | $82,067 | $102,532 | $6839 | $8544 |
| 2500–3400 g | 984 | 40.0 | 5.3 | 17.3 | $83,658 | $104,124 | $6972 | $8677 |
| 2500–3500 g | 1039 | 40.7 | 5.3 | 17.3 | $86,338 | $106,803 | $7195 | $8900 |
| 2500–3600 g | 1060 | 42.0 | 5.3 | 17.3 | $87,343 | $107,808 | $7279 | $8984 |
| 2500–3700 g | 1072 | 42.0 | 5.3 | 17.3 | $87,929 | $108,395 | $7327 | $9033 |
| 2500–3800 g | 1078 | 42.0 | 5.3 | 17.3 | $88,223 | $108,688 | $7352 | $9057 |
| 2500–3900 g | 1083 | 42.0 | 5.3 | 17.3 | $88,432 | $108,897 | $7369 | $9075 |
| 2500–4000 g | 1096 | 42.0 | 5.3 | 17.3 | $89,060 | $109,525 | $7422 | $9127 |
BW, birthweight; GA, gestational age.
Coyle et al. Cost analysis of a gestational age algorithm. AJOG MFM 2021.