Table 4.
Association of expression of the circulating lncRNA MIAT with different parameters among patients with T2DM
| Variable | Fold change in MIAT expression among patients with T2DM (mean±SD) | P value |
| Overall expression | 6.35±2.72 | – |
| Age (years) | ||
| ≤40 years | 3.58±3.53 | 0.12 |
| >40 years | 4.44±3.94 | |
| Sex | ||
| Male | 4.10±3.56 | 0.63 |
| Female | 4.44±3.94 | |
| Hypertension | ||
| Yes | 4.32±3.77 | 0.66 |
| No | 4.15±6.69 | |
| Nephropathy | ||
| Yes | 4.45±3.89 | 0.43 |
| No | 4.07±3.59 | |
| Weight loss | ||
| Yes | 4.20±3.93 | 0.53 |
| No | 4.31±3.57 | |
| Fatigue | ||
| Yes | 4.78±4.09 | 0.10 |
| No | 3.78±3.32 | |
| Slow wound healing | ||
| Yes | 4.08±3.66 | 0.38 |
| No | 4.50±3.84 | |
| Retinopathy | ||
| Yes | 5.32±3.72 | <0.0001 |
| No | 3.72±3.79 | |
| Loss of appetite | ||
| Yes | 4.25±3.50 | 0.69 |
| No | 4.26±3.93 | |
| Smoking | ||
| Yes | 5.41±3.36 | <0.0001 |
| No | 3.27±9.73 | |
| Alcoholism | ||
| Yes | 5.74±3.28 | <0.0001 |
| No | 2.71±3.55 | |
lncRNA, long non-coding RNA; MIAT, myocardial infarction-associated transcript; T2DM, type 2 diabetes mellitus.