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. 2021 Jan 13;129(1):017002. doi: 10.1289/EHP7310

Table 1.

Characteristics, self-reported symptoms and diseases, and FLG null frequencies among the study participants.

Characteristic n (%) n (%) p-Valuea
FLG null (n=23) FLG wt (n=31)
Age (mean±SD) 39.6±15.0 38.8±15.3 0.45
BMI (mean±SD) 24.4±5.8 24.1±4.6 0.62
Sex
 Male 10 (43.5) 12 (38.7) 0.72
 Female 13 (56.5) 19 (61.7)
Smoking
 Passive smoker 0 (0) 3 (9.7) 0.12
 Party smoker 2 (8.7) 1 (3.2) 0.38
 Previous smoker 8 (34.8) 9 (29.0) 0.57
Rash 4 (17.4) 7 (22.6) 0.64
Allergy symptoms, nose 14 (60.9) 12 (38.7) 0.20
Allergy symptoms, eyes 15 (65.2) 12 (38.7) 0.13
Asthma 4 (17.4) 3 (9.7) 0.40
Hand eczema 7 (30.4) 5 (16.1) 0.21
Wrist/forearm eczema 4 (17.4) 5 (16.1) 0.90
Dry skin 15 (65.2) 17 (54.8) 0.31
Childhood eczema 6 (26.1) 8 (25.8) 0.98
Nickel allergy 1 (4.3) 6 (19.4) 0.21
FLG null genotype
 R501X 8 (34.7) 0 NA
 R2447X 2 (8.7) 0 NA
 S3247X 3 (13.0) 0 NA
 2282del4 10 (43.5) 0 NA

Note: p-Values represent differences between FLG null and wt carriers. —, no data; BMI, body mass index; SD, standard deviation; NA, not applicable.

a

For continuous variables: Student’s t-test, for categorical variables: chi-square test.