Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
(a) The contents of the asymmetric unit are shown with chain A in cyan and chain B in violet. Between the two monomers one can see the domain swapping of the activation loop. (b) Superposition of the two monomers (chain A in cyan and chain B in violet) showing that with the exception of the position of the αC-helix and surrounding residues, the activation loop and the extended C-terminus of chain A, the chains follow the same path.
