Table 3.
Microsomal stability of 1d
| Compounds | Mouse | Human | ||
|---|---|---|---|---|
| (% remaining at 30 min) | ||||
| With NADPH | Without NADPH | With NADPH | Without NADPH | |
| Macozinone | 50.7 | 102 | 46.8 | 101 |
| 1d | 38.6 | 96.4 | 26.3 | 102 |
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