eTable 2. Heat threshold and thermal optimum by region and age group (mean for the segments 1992–2000, 2001–2010, and 2011–2017)*.

	Age group
Region	< 65	65–74	75–84	85+
Thermal optimum
Northern	15.1	16.4	16.9	16.0
Central	17.4	18.3	18.5	17.3
Southern	14.5	17.6	17.5	17.2
Heat threshold
Northern	–	–	19.2	19.0
Central	20.9	20.4	20.0	19.8
Southern	–	20.8	20.5	20.3

* For some combinations no threshold for heat can be determined, because the corresponding exposure–response curve for the mean temperature of the preceding week is monotonic and therefore features no local minimum.