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. 2020 Oct 29;143(12):3763–3775. doi: 10.1093/brain/awaa334

Table 1.

Sample characteristics of the training (cortex), testing (cortex), independent test (cortex) and whole blood datasets used in the development and evaluation of DNAmClockCortical

Dataset Age, years
Sex, n
Illumina methylation array References
n Mean 1st Quartile Median 3rd Quartile Range Female Male
Training 1047 56.53 38.56 57 78 1–108 362 685 450K De Jager et al., 2014; Lunnon et al., 2014; Pidsley et al., 2014; Jaffe et al., 2016; Smith et al., 2018, 2019; Wong et al., 2019
Testing 350 55.87 39.05 56 78 1–108 144 206 450K De Jager et al., 2014; Lunnon et al., 2014; Pidsley et al., 2014; Jaffe et al., 2016; Smith et al., 2018, 2019; Wong et al., 2019
Independent test 1221 83.49 78 84 90 41–104 577 644 EPIC
Blood 1175 57.96 46 59 69 28–98 686 489 EPIC Hannon et al., 2018