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. 2018 Nov 2;5:120. doi: 10.3389/frobt.2018.00120

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Copyright © 2018 Cenek, Hu, York and Dahl.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Illustration of features extracted and used by either a radiologist or a computer algorithm. The left images shows the original MRI image, with the annotated features of interest on the right. A: tumor, B: hematoma, C: calcium deposit, D: the volume decrease in the images brain tissue, E: the volume increase with respect to expected and F: a tissue inflammation. The green contour line associated with features D,E shows the expected (normal) shape of the imaged soft tissue and the red contour shows the actual shape.