Table 2. Clinical details, MIC distribution, and mutation status of the azole resistant isolates.
| NCCPF ID | GenBank accession number | Source of isolates | Flu MIC (mg/L) | Vori MIC (mg/L) | Itra MIC (mg/L) | Posa MICs (mg/L) | ERG11 mutations | Amino acid alterations |
|---|---|---|---|---|---|---|---|---|
| 420189 | MW015956 | Blood | 128 | 4 | 0.5 | 0.5 | A395T & C461T | Y132F & S154F |
| 420227 | MW015957 | Pus | 128 | 0.5 | 0.25 | 0.5 | A395T & C461T | Y132F & S154F |
| 420232 | MW015958 | Blood | 32 | 0.5 | 0.5 | 0.5 | A395T & C461T | Y132F & S154F |
| 420233 | MW015959 | Blood | 32 | 1 | 0.25 | 0.25 | A395T & C461T | Y132F & S154F |
| 420234 | MW015960 | Blood | 64 | 1 | 0.25 | 0.25 | A395T & C461T | Y132F & S154F |
| 420235 | MW015961 | Blood | 32 | 0.5 | 0.25 | 0.25 | A395T & C461T | Y132F & S154F |
| 420236 | MW015962 | Blood | 32 | 0.5 | 0.25 | 0.25 | A395T & C461T | Y132F & S154F |
| 420237 | MW015963 | Blood | 64 | 1 | 0.5 | 0.5 | A395T & C461T | Y132F & S154F |
| 420238 | MW015964 | Ascitic fluid | 256 | 16 | 16 | 2 | A395T & C461T | Y132F & S154F |
| 420239 | MW015965 | Blood | 256 | 16 | 16 | 0.5 | A395T & C461T | Y132F & S154F |
| 420245 | MW015966 | Blood | 128 | 4 | 1 | 0.5 | A395T & C461T | Y132F & S154F |
| 420247 | MW015967 | Wound slough | 128 | 4 | 2 | 0.25 | A395T & C461T | Y132F & S154F |
Flu: Fluconazole; Vori: Voriconazole; Itra: Itraconazole; Posa: Posaconazole; Y: Tyrosine; F: Phenylalanine; S: Serine