Table 1. Taxonomic distribution of BON family domain architectures.
| Cluster number* | UniRef100† | Total number of proteins ‡ |
Major domain architecture in cluster§ | α | β | γ | δ | ε | ζ | Aci†† | Act†† | Bac†† | Chl†† | Chl†† | Chl†† | Cya†† | Dei†† | Fib†† | Fir†† | Gem†† | Nit†† | Pla†† | Spi†† | Syn†† | The†† | The†† | The†† | Ver†† |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 1280 | 2723 | OsmY-like and 1 x BON | 41 (89)¶,** | 176 (533) | 1484 (1830) | 33 (56) | 12 (12) | 1 (1) | 6 (12) | 2 (3) | 5 (5) | 3 (11) | 3 (4) | 43 (65) | 1 (1) | 13 (13) | 1 (2) | 1 (1) | 14 (30) | 9 (9) | 1 (1) | 1 (1) | 7 (19) | ||||
| 2 | 833 | 2395 | DolP-like | 97 (103) | 330 (335) | 1892 (1919) | 15 (17) | 2 (2) | 1 (1) | 1 (2) | 1 (1) | |||||||||||||||||
| 3 | 579 | 690 | three x BON + 1 x BON | 95 (187) | 108 (255) | 35 (36) | 18 (28) | 7 (23) | 14 (25) | 14 (30) | 2 (2) | 3 (21) | 6 (10) | 5 (7) | 1 (1) | 32 (32) | 1 (2) | 12 (27) | 1 (1) | |||||||||
| 4 | 476 | 537 | BON + secretin | 207 (276) | 77 (80) | 70 (117) | 32 (34) | 4 (4) | 1 (1) | 3 (3) | 10 (11) | 1 (1) | 7 (7) | 1 (1) | ||||||||||||||
| 5 | 409 | 1570 | Kbp-like | 66 (66) | 131 (132) | 1323 (1328) | 1 (1) | 1 (1) | 31 (31) | 5 (5) | 1 (1) | 1 (1) | ||||||||||||||||
| 6 | 282 | 300 | CBS + CBS + BON | 82 (136) | 17 (29) | 4 (4) | 53 (127) | 4 (4) | ||||||||||||||||||||
| 7 | 220 | 318 | BON + BON + OmpA | 157 (161) | 55 (57) | 9 (11) | 62 (64) | 1 (1) | 19 (23) | 1 (1) | ||||||||||||||||||
| 8 | 70 | 75 | BON + Mschannel | 31 (32) | 1 (1) | 24 (25) | 2 (3) | 1 (1) | 8 (13) | |||||||||||||||||||
| 9 | 52 | 52 | one x BON | 1 (1) | 42 (51) | |||||||||||||||||||||||
| 10 | 43 | 80 | one x BON and 1 x DUF2204 | 1 (1) | 1 (1) | 77 (77) | 1 (1) | |||||||||||||||||||||
| 11 | 33 | 87 | 1–2 X Forkhead + BON | 2 (2) | 4 (4) | 2 (2) | 78 (79) | |||||||||||||||||||||
| 12 | 30 | 33 | one x BON | 26 (27) | 3 (3) | 1 (1) | 1 (1) | 1 (1) | ||||||||||||||||||||
| smaller cluster/unclustered: | ||||||||||||||||||||||||||||
| 83 | 109 | 22 (29) | 19 (19) | 25 (25) | 9 (9) | 1 (1) | 4 (12) | 2 (2) | 1 (1) | |||||||||||||||||||
* The main twelve clusters were analysed, all proteins falling into smaller clusters were summarised into the single category ‘smaller cluster’.
†, ‡, §, ¶ Shown are the number of UniRef100 used in the clustering approach†, the corresponding number of proteins derived from the HMMER search‡, the observed major domain architecture§ and the number of unique protein sequences (in brackets)¶ as well as the number of unique organisms mapped to the bacterial (Sub)Phyla**.
†† Acidobacteria, Actinobacteria, Bacteroidetes, Chlamydiae, Chlorobi, Chloroflexi, Cyanobacteria, Deinococcus-Thermus, Fibrobacteres, Firmicutes, Gemmatimonadetes, Nitrospirae, Planctomycetes, Spirochaetes, Synergistetes, Thermobaculum, Thermodesulfobacteria, Thermotogae, Verrucomicrobia.