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. 2021 Jan 6;2021:3210586. doi: 10.1155/2021/3210586

Figure 5.

Figure 5

The effect of IRSp53 on HUVEC mobility. (a) Representative images of a scratch assay of HUVECs with different treatments (100x magnification) and the wound closure rate of HUVECs with different treatments. (b) Representative images of a transwell assay of HUVECs with different treatments (200x magnification) and the number of migrated cells. NC: normal control; OE-IRSp53: overexpressing IRSp53; SI-IRSp53: knockdown IRSp53; normal glucose (25 mM); HG: high glucose (60 mM); HG+INS: high glucose (60 mM) + insulin (1.5 μg/mL). The values are the mean ± SD of three independent experiments. ∗∗∗P < 0.001 vs. the NG group; #P < 0.05 vs. the HG group; ##P < 0.01 vs. the HG group; ###P < 0.001 vs. the HG group; †††P < 0.001.