Skip to main content
. 2021 Jan 6;2021:6616240. doi: 10.1155/2021/6616240

Figure 7.

Figure 7

CAB39 alleviates miR-34a-3p-induced senescence in DPSCs through the AMPK/mTOR signaling pathway. Aging DPSCs were pretransfected with miR-34a-3p mimics or miR-NC for 5 h, prior to transfection with Lenti-CAB39 or vehicle control for 48 h. (a) Representative images of SA-β-gal staining and (b) quantitative analysis of SA-β-gal-positive cells (scale bar: 20 μm). (c) Representative blots and (d) quantitative analysis of the expression levels of p53, p21, and p16. (e) Representative blots of the expression levels of p-AMPK, AMPK, p-mTOR, and mTOR. (f) Quantitative analysis of p-AMPK/AMPK and p-mTOR/mTOR ratios. Data are expressed as mean ± standard deviation (n = 3). NS: not significantly different. ∗∗p < 0.01, with comparisons indicated by lines.