Table 2.
Analysis of the percentage and absolute numbers of leukocyte and total lymphocytes as well as percentages of activated CD3+CD154+ T cell subsets during the first year post‐transplantation
| Follow‐up period | LTr (N = 30) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Leukocyte (×109/l) | Total lymphocyte (cells/mm3) | Total lymphocyte (%) | CD4+CD154+ T cells (%) | CD8+CD154+ T cells (%) | |||||||||||
| ACR (n = 12) | NACR (n = 18) | P | ACR (n = 12) | NACR (n = 18) | P | ACR (n = 12) | NACR (n = 18) | P | ACR (n = 12) | NACR (n = 18) | P | ACR (n = 12) | NACR (n = 18) | P | |
| 7 days | 10·75 ± 1·02 | 13·17 ± 1·53 | 0·325 | 1066·38 ± 192·79 | 1766·67 ± 464·14 | 0·249 | 9·49 ± 1·22 | 12·42 ± 2·04 | 0·465 | 2·39 ± 0·56 | 0·87 ± 0·09 | <0·001 | 1·22 ± 0·07 | 0·67 ± 0·09 | < 0·001 |
| 15 days | 9·85 ± 0·97 | 8·94 ± 0·87 | 0·303 | 1125·00 ± 137·69 | 1644·39 ± 514·90 | 0·819 | 11·31 ± 0·72 | 13·77 ± 1·82 | 0·616 | 2·21 ± 0·43 | 0·99 ± 0·11 | 0·01 | 1·25 ± 0·12 | 0·76 ± 0·08 | 0·004 |
| 30 days | 7·31 ± 0·89 | 7·40 ± 0·74 | 0·647 | 1058·34 ± 156·41 | 1977·72 ± 526·29 | 0·346 | 15·83 ± 2·49 | 21·55 ± 2·57 | 0·195 | 1·51 ± 0·23 | 1·13 ± 0·28 | 0·08 | 1·04 ± 0·15 | 1·02 ± 0·10 | 0·819 |
| 60 days | 6·50 ± 0·60 | 6·59 ± 0·59 | 0·605 | 2798·17 ± 987·69 | 3141·78 ± 768·90 | 0·723 | 22·14 ± 4·00 | 27·84 ± 2·32 | 0·367 | 3·78 ± 1·92 | 6·48 ± 2·26 | 0·435 | 3·70 ± 1·12 | 4·60 ± 1·51 | 0·943 |
| 90 days | 5·83 ± 0·81 | 6·13 ± 0·89 | 0·976 | 2789·84 ± 987·72 | 4022·50 ± 912·87 | 0·172 | 24·87 ± 2·83 | 31·05 ± 2·53 | 0·101 | 6·73 ± 2·24 | 4·43 ± 1·79 | 0·222 | 5·37 ± 1·12 | 4·32 ± 1·23 | 0·435 |
| 180 days | 4·77 ± 0·64 | 6·26 ± 0·79 | 0·167 | 5166·25 ± 1237·54 | 4585·78 ± 943·01 | 0·755 | 33·14 ± 2·55 | 31·47 ± 2·89 | 0·592 | 5·43 ± 1·75 | 4·72 ± 1·20 | 0·943 | 6·93 ± 2·59 | 5·13 ± 1·03 | 0·833 |
| 365 days | 5·22 ± 0·66 | 6·96 ± 0·89 | 0·279 | 6574·42 ± 1224·11 | 4671·89 ± 924·95 | 0·439 | 34·40 ± 1·86 | 31·50 ± 3·69 | 0·574 | 8·21 ± 2·71 | 10·79 ± 3·73 | 0·921 | 8·38 ± 4·03 | 8·88 ± 2·29 | 0·921 |
N = total number of individuals; n = number of patients in each group; LTr = liver transplant recipients; ACR = acute cellular rejection; NACR = non‐acute cellular rejection; s.e.m. = standard error of the mean. All comparisons were made between ACR and NACR groups.
P = P‐values obtained by the univariate analysis between total ACR (n = 12) versus NACR (n = 18) liver patient groups. Data were compared by the two‐sided Mann–Whitney test and are expressed as mean ± s.e.m. Statistically significant P‐values are denoted in bold type.