Figure 2.

Assessing doxorubicin release under FUS, measured by intrinsic doxorubicin fluorescence; (A) schematic showing a polyacrylamide gel embedded flow-tube below a focused ultrasound transducer (Figure S1); (B) graphs of thermocouple (left) and fluorescence intensity (right) readings seen with increasing power levels of constantly applied FUS, using a fresh bolus of iTSL-DOX for each 2 min insonation; (C) Fluorescence intensity and temperature plotted against time under pulsed FUS and constant iTSL-DOX flow.