Figure 5.

Spin-echo transverse T₁ weighted MR imaging, iTSL (1.37 mg/mL gadolinium) was injected (i.v. tail vein) to mice, (A) Imaging (9.4 T) of the same representative animal pre-injection, then 1 h, 3 h, and 5 h post-injection. T₁-weighted tumours images are overlaid with T₁ relaxivity maps (in false colour) for the region-of-interest (ROI), as indicated with arrows; (B) Comparative T₁ values for selected volumes-of-interest (combining the ROIs from matched slices) from a single-tumour mouse study (n = 3; individual values •, mean as horizontal bar, SD as vertical bar); see also Figure S7. A lower T₁ implies a stronger contrast enhancement.