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. 2021 Jan 1;11(6):2634–2654. doi: 10.7150/thno.53139

Figure 5.

Figure 5

D-Nap-GFFY-T317 protects both WT and IFNγ-/- mice against T317-induced hepatic lipid accumulation. At the end of treatment, serum and liver samples collected from mice used in Figure 2B-D were used to conduct the following assays. (A) liver photos. (B) ratio of liver weight to body weight. (C) Oil Red O staining of liver frozen sections. (D) TG quantitative analysis with total liver lipid extract (n = 5). Expression of LXRα and LXRβ (E), FASN and nSREBP1 (F) protein in the liver was determined by Western blot. (G) serum TG levels were determined using an assay kit (n = 5). *P < 0.05, **P < 0.01, ***P < 0.001 vs. control or as indicated, ^P < 0.05 vs. TF.