Table 1.
Study characteristics at baseline and primary conclusion.
Author | Arm | Age | NIV/HF n/N (%) | MV/ECMO n/N (%) | Conclusion |
---|---|---|---|---|---|
Beigel et al. [14] | Control | 59.2 ± 15.4 | 98/521 (18.8%) | 154/521 (29.6%) | RDV reduced the time to recovery in COVID-19 patients. |
RDV | 58.6 ± 14.6 | 95/541 (17.6%) | 131/541 (24.2%) | ||
Spinner et al. [13] | Control | 57 (45–66) | 2/200 (1%) | 0/200 (0%) | RDV (5D) improved clinical status in COVID-19 patients as compared to control at day 11. |
RDV (5D) | 58 (48–66) | 2/191 (1%) | 0/191 (0%) | ||
RDV (10D) | 56 (45–66) | 1/193 (1) | 0/193 (0%) | ||
Wang et al. [7] | Control | 64 (53–70) | 9/78 (12%) | 1/78 (1%) | RDV did not improve clinical status of COVID-19 patients |
RDV | 66 (57–73) | 28/158 (18%) | 0/158 (0%) |
Age is expressed as mean ± standard deviation or median (interquartile range). RDV = remdesivir; NIV = noninvasive ventilation; HF = high flow oxygen; MV = mechanical ventilation; ECMO = extracorporeal membrane oxygenation; 5D = 5 day; 10D = 10 day.