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. 2021 Jan 6;62:43–48. doi: 10.1016/j.amsu.2020.12.051

Table 1.

Study characteristics at baseline and primary conclusion.

Author Arm Age NIV/HF n/N (%) MV/ECMO n/N (%) Conclusion
Beigel et al. [14] Control 59.2 ± 15.4 98/521 (18.8%) 154/521 (29.6%) RDV reduced the time to recovery in COVID-19 patients.
RDV 58.6 ± 14.6 95/541 (17.6%) 131/541 (24.2%)
Spinner et al. [13] Control 57 (45–66) 2/200 (1%) 0/200 (0%) RDV (5D) improved clinical status in COVID-19 patients as compared to control at day 11.
RDV (5D) 58 (48–66) 2/191 (1%) 0/191 (0%)
RDV (10D) 56 (45–66) 1/193 (1) 0/193 (0%)
Wang et al. [7] Control 64 (53–70) 9/78 (12%) 1/78 (1%) RDV did not improve clinical status of COVID-19 patients
RDV 66 (57–73) 28/158 (18%) 0/158 (0%)

Age is expressed as mean ± standard deviation or median (interquartile range). RDV = remdesivir; NIV = noninvasive ventilation; HF = high flow oxygen; MV = mechanical ventilation; ECMO = extracorporeal membrane oxygenation; 5D = 5 day; 10D = 10 day.