Table 1.
Sample source | Expected dystrophin expression | Gadolinium concentrationa | CV |
---|---|---|---|
WT mouse | Normal | 736b,c | 10b |
mdx mouse | Absent | 85.0 | 20.5 |
Healthy 1 | Normal | 382b,c | 19b |
Healthy 2 | Normal | 286b | 17b |
DMD 1 | Low | 99.2 | nad |
DMD 2 | Low | 86.5 | nad |
DMD 3 | Very low | < LLOQ | nad |
DMD 4 | Low | 100 | nad |
LLOQ lower limit of quantification.
aµg kg−1 gadolinium.
bn = 7 consecutive muscle sections.
cOutlier removed after Grubb’s test (gcrit = 1.938 for n = 7).
dSingle sections were analyzed from these samples so CV is not applicable (na).