Fig. 5. Germ cells versus in utero environment in the transmission of anxiety like phenotype in offspring.

A Schematic illustration showing prepubertal mouse model and generation of F₁ and F₂ offspring by using IVF. B–D Time spent in the open arms in the elevated plus maze (EPM); time spent in the closed arms of the EPM; time spent in the center of the open filed (OF); time spent in the periphery of the OF. Data were analyzed with Student’s t-test. All data are presented as mean ± s.e.m. CNT control, DHT dihydrotestosterone.