Fig. 4.

Wound healing effects on impaired of mouse skin. a Wounds of 5 mm diameter were created on the dorsal skin of 7 weeks of age Male C57Bl/6 mice. Before the procurement of wound biopsies at specific time points (non-treated and post-treated mg/ml 10, 25, 50). b Wound area was determined by measuring the diameter of open wounds. c Wound area was calculated using the distance of open wounds. **p < 0.01, 0 mg/ml versus 10 mg/ml samples; ##p < 0.01, 0 mg/ml versus 50 mg/ml samples