Table 1.
Minimum inhibitory concentration (MIC) of drugs and the results of cytotoxicity studies.
| Drugs | Mtb H37Rv strain | Mtb H37Rv strain (freshly passaged from guinea pig) | Cytotoxicityb | ||
|---|---|---|---|---|---|
| 1 µg/mL | 0.5 µg/mL | 1 µg/mL | 0.5 µg/mL | ||
| RIF | (Inhibited) | Scantya | (Inhibited) | Scantya | 87 µg/mL |
| Phenazine(4) | (No Inhibition) | (No Inhibition) | (No Inhibition) | (No Inhibition) | – |
| RPZ (5) | (Inhibited) | (Inhibited) | (Inhibited) | Scantya | 96 µg/mL |
aAble to see the growth of very few countable colonies.
b(IC50 on human monocytic cell line THP-1).