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. 2021 Jan 13;11:865. doi: 10.1038/s41598-020-79608-0

Figure 2.

Figure 2

Serum levels of four different biomarkers reflecting (A) formation of collagen type III (PRO-C3), (B) formation of collagen type VI (PRO-C6), (C) degradation of collagen type VIα1 (C6M) and (D) degradation of collagen type VIα3 (C6Mα3) in patients with metastatic colorectal cancer with their respective reference range from healthy controls (dotted line). Black line, median. LLOD; lower limit of detection.