Table 1.
Results of the ddPCR assay to identify the CNA of the TRPM7 and MDM2 genes in tumors and plasma of dogs with OMM.
| Dog Id | Tumor | cfDNA |
|---|---|---|
| Gain detected: copy number (95% confidence interval) | Gain detected: copy number (95% confidence interval) | |
| 19006 | TRPM7: 37.90 (28.41–47.39) | TRPM7: 2.80 (2.58–3.03) |
| 18394 | TRPM7: 7.98 (7.71–8.25) | No |
| 18657 | TRPM7: 3.01 (2.89–3.14) | No |
| 18718 | MDM2: 21.26 (19.37–23.15) | MDM2: 3.02 (2.19–3.85) |
| TRPM7: 7.46 (7.17–7.75) | No | |
| 18395 | MDM2: 52.96 (45.74–60.17) | No |
| TRPM7: 8.78 (8.37–9.19) | No | |
| 18303 | TRPM7: 8.88 (8.55–9.20) | No |
| 18333 | MDM2: 4.30 (3.91–4.68) | No |
| TRPM7: 27.24 (25.94–28.54) | No | |
| 18848 | TRPM7: 9.12 (8.78–9.46) | No |
Eight dogs had at least one gene amplified in their tumors, and two dogs had a copy number imbalance in the plasma.