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GLP-1-Fc-FGF21 mutant fusion proteins. D1, D2 and D3 were constructed by linking S1, S2 and S3 mutants with GLP-1, respectively.
| GLP-1-Fc-FGF21 mutants | GLP-1-Fc-FGF21 mutants ID |
|---|---|
| GLP-1-Fc-FGF21 (L98R, S167H, P171A, R175L) | D1 |
| GLP-1-Fc-Fc-FGF21 (L98R, S167H, P171A, R175P) | D2 |
| GLP-1-Fc-Fc-FGF21 (L98R, S167H, P171A) | D3 |
