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. 2021 Jan 13;11:947. doi: 10.1038/s41598-020-80363-5

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Input 3a, and output 3b of the methodology in colored pixels represent bases: G = green, C = blue, A = red, T = orange, missing = black. The data is separated by class SARS-CoV1: SARS-CoV, SARS-CoV P2, SARS-CoV HKU-39849 and SARS-CoV GDH-BJH01. For visualization purposes we do not show HCov-EMC and HCoV-4408, given the number of samples. From visual inspection, it is possible to notice the similarity of patterns between samples belonging to the same class.