Table 3.
Summary of assessed variables for prediction of death versus recovery from COVID-19 pneumonia in patients from Site B.
| Outcomes | p value | AUC (95% CI) [OR] |
||
|---|---|---|---|---|
| Death | Recovery | |||
| (n = 49) | (n = 130) | |||
| Age (mean ± SD, years) | 75 ± 9 | 59 ± 17 | < 0.001 | 0.78 (0.69–0.86) |
| Male/Female | 31/18 [63%/37%] | 57/73 [44%/56%] | 0.020 | [2.2] |
| BMI | 24.4 ± 4.1 | 23.8 ± 2.7 | 0.423 | 0.55 (0.41–0.70) |
| SpO2 | 94.1 ± 8.2 | 97.0 ± 3.1 | 0.018 | 0.48 (0.32–0.64) |
| Temperature (Celsius) | 36.9 ± 0.7 | 36.9 ± 0.7 | 0.788 | 0.49 (0.35–0.62) |
| Total WBC count | 8911.1 ± 4349.1 | 5853.7 ± 2094.1 | < 0.001 | 0.76 (0.64–0.89) |
| Platelet count | 205.1 ± 97.8 | 229.2 ± 87.7 | 0.120 | 0.37 (0.24–0.50) |
| CRP | 25.2 ± 31.8 | 16.9 ± 28.2 | 0.103 | 0.68 (0.59–0.77) |
| Baseline RALE | 15.6 ± 8.4 | 4.1 ± 6.2 | < 0.001 | 0.87 (0.81–0.93) |
| Max RALE | 29.8 ± 10.1 | 6.3 ± 7.9 | < 0.001 | 0.95 (0.91–0.99) |
| Baseline AI score | 100.6 ± 39.8 | 40.7 ± 47.8 | < 0.001 | 0.82 (0.76–0.89) |
| Max AI score | 149.2 ± 25.3 | 61.4 ± 55.6 | < 0.001 | 0.91 (0.86–0.96) |
| RALE score change | 13.9 ± 10.2 | 2.3 ± 4.2 | < 0.001 | 0.86 (0.79–0.93) |
| AI score change | 45.6 ± 37.1 | 20.6 ± 26.8 | < 0.001 | 0.72 (0.63–0.81) |
Maximum RALE and AI scores were the strongest predictors of final patient outcome.
SD standard deviation, BMI body mass index, SpO2 peripheral oxygen saturation, CRP c-reactive protein, max maximum, AUC area under the curve, CI confidence interval, OR odd’s ratio, % percentage.
Numbers in square parenthesis represent odd’s ratios (R2-14).