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. 2021 Jan 13;11:858. doi: 10.1038/s41598-020-79470-0

Table 3.

Summary of assessed variables for prediction of death versus recovery from COVID-19 pneumonia in patients from Site B.

Outcomes p value AUC (95% CI)
[OR]
Death Recovery
(n = 49) (n = 130)
Age (mean ± SD, years) 75 ± 9 59 ± 17  < 0.001 0.78 (0.69–0.86)
Male/Female 31/18 [63%/37%] 57/73 [44%/56%] 0.020 [2.2]
BMI 24.4 ± 4.1 23.8 ± 2.7 0.423 0.55 (0.41–0.70)
SpO2 94.1 ± 8.2 97.0 ± 3.1 0.018 0.48 (0.32–0.64)
Temperature (Celsius) 36.9 ± 0.7 36.9 ± 0.7 0.788 0.49 (0.35–0.62)
Total WBC count 8911.1 ± 4349.1 5853.7 ± 2094.1  < 0.001 0.76 (0.64–0.89)
Platelet count 205.1 ± 97.8 229.2 ± 87.7 0.120 0.37 (0.24–0.50)
CRP 25.2 ± 31.8 16.9 ± 28.2 0.103 0.68 (0.59–0.77)
Baseline RALE 15.6 ± 8.4 4.1 ± 6.2  < 0.001 0.87 (0.81–0.93)
Max RALE 29.8 ± 10.1 6.3 ± 7.9  < 0.001 0.95 (0.91–0.99)
Baseline AI score 100.6 ± 39.8 40.7 ± 47.8  < 0.001 0.82 (0.76–0.89)
Max AI score 149.2 ± 25.3 61.4 ± 55.6  < 0.001 0.91 (0.86–0.96)
RALE score change 13.9 ± 10.2 2.3 ± 4.2  < 0.001 0.86 (0.79–0.93)
AI score change 45.6 ± 37.1 20.6 ± 26.8  < 0.001 0.72 (0.63–0.81)

Maximum RALE and AI scores were the strongest predictors of final patient outcome.

SD standard deviation, BMI body mass index, SpO2 peripheral oxygen saturation, CRP c-reactive protein, max maximum, AUC area under the curve, CI confidence interval, OR odd’s ratio, % percentage.

Numbers in square parenthesis represent odd’s ratios (R2-14).