Table 4.

Summary of assessed variables for predicting need for mechanical ventilation in patients from Site B.

	Mechanical ventilation		p value	AUC (95% CI) [OR]
	Yes	No
	(n = 32)	(n = 147)
Age (mean ± SD, years)	66.7 ± 10.3	62.1 ± 17.9	0.056	0.56 (0.48–0.65)
Male/Female	20/12 [62%/38%]	68/79 [46%/54%]	0.096	[1.9]
BMI	25.7 ± 3.5	23.5 ± 2.7	< 0.001	0.64 (0.51–0.77)
SpO2	93.0 ± 9.5	96.9 ± 3.3	0.031	0.41 (0.25–0.56)
Temperature (Celsius)	37.1 ± 0.7	36.9 ± 0.7	0.195	0.55 (0.42–0.68)
Total WBC count	9135.6 ± 4266.1	6160.5 ± 2632.2	0.001	0.75 (0.62–0.87)
Platelet count	217.7 ± 83.6	223.9 ± 92.7	0.729	0.53 (0.39–0.67)
CRP	23.0 ± 25.8	18.3 ± 30.1	0.429	0.71 (0.61–0.80)
Baseline RALE	15.2 ± 9.1	5.5 ± 7.4	< 0.001	0.81 (0.73–0.88)
Max RALE	27.7 ± 9.9	9.0 ± 11.5	< 0.001	0.88 (0.83–0.93)
Baseline AI score	100.9 ± 38.1	47.6 ± 50.9	< 0.001	0.79 (0.71–0.86)
Max AI score	145.7 ± 24.1	70.5 ± 60.6	< 0.001	0.84 (0.79–0.90)
RALE score change	12.5 ± 10.1	3.7 ± 6.6	< 0.001	0.79 (0.70–0.88)
AI score change	44.7 ± 38.7	23.1 ± 28.6	< 0.001	0.68 (0.57–0.78)

Maximum RALE and AI scores were the strongest predictors of need for mechanical ventilation.

SD standard deviation, BMI body mass index, SpO₂ peripheral oxygen saturation, CRP c-reactive protein, max maximum, AUC area under the curve, CI confidence interval, OR odd’s ratio, % percentage.

Numbers in square parenthesis represent odd’s ratios (R2-14).