Table 1.
Description of the sample.
| Variables | Categories | Patients without DRP | Patients with DRP | Total sample | p value |
|---|---|---|---|---|---|
| Gender (n, %) | Female | 408 (46.4) | 310 (42.9) | 718 (44.8) | 0.170 |
| Male | 472 (53.6) | 412 (57.1) | 884 (55.2) | ||
| Age (years; mean, SD) | 72.67 (15.20) | 72.92 (14.97) | 72.78 (15.09) | 0.747 | |
| Country (n, %) | Spain | 838 (95.2) | 694 (96.1) | 1532 (95.6) | 0.383 |
| Other | 42 (4.8) | 28 (3.9) | 70 (4.4) | ||
| Allergy (n, %) | Yes | 176 (20.0) | 180 (24.9) | 356 (22.2) | 0.018 |
| No | 704 (80.0) | 542 (75.1) | 1246 (77.8) | ||
| BMI (n, %) | < 18 | 212 (24.5) | 155 (21.6) | 367 (23.1) | 0.003 |
| 18–25 | 529 (61.0) | 413 (57.4) | 942 (59.4) | ||
| ≥ 25 | 126 (14.5) | 151 (21.0) | 277 (17.5) | ||
| Polypharmacy (mean, SD) | 7.65 (4.65) | 8.77 (4.71) | 8.15 (4.71) | 0.000 | |
| Missing information (n, %) | Yes | 25 (2.8) | 22 (3.0) | 47 (2.9) | 0.808 |
| No | 855 (97.2) | 700 (97.0) | 1555 (97.1) | ||
| Hepatic impairment (n, %) | Yes | 95 (10.8) | 83 (11.5) | 178 (11.1) | 0.306 |
| No | 785 (89.2) | 635 (88.5) | 1424 (88.9) | ||
| Renal function (n, %) | < 30 | 124 (14.2) | 123 (17.1) | 247 (15.5) | 0.148 |
| 30–60 | 282 (32.3) | 242 (33.7) | 524 (32.9) | ||
| ≥ 60 | 468 (53.5) | 354 (49.2) | 822 (51.6) | ||
| NCC (mean, SD) | 5.76 (3.01) | 6.27 (3.09) | 5.99 (3.06) | 0.001 | |
| Coming from NH (n, %) | Yes | 76 (8.6) | 65 (9.0) | 141 (8.8) | 0.802 |
| No | 803 (91.4) | 657 (91.0) | 1460 (91.2) | ||
| Last 12 months HA (n, %) | Yes | 365 (41.5) | 347 (48.1) | 712 (44.4) | 0.008 |
| No | 515 (58.5) | 375 (51.9) | 890 (55.6) | ||
| Department (n, %) | Digestive | 80 (9.1) | 72 (10.0) | 152 (9.5) | 0.828 |
| Geriatrics | 195 (22.2) | 166 (23.0) | 361 (22.5) | ||
| Internal Medicine | 253 (28.8) | 198 (27.4) | 451 (28.2) | ||
| Neurology | 181 (20.6) | 137 (19.0) | 318 (19.9) | ||
| Respiratory | 171 (19.4) | 149 (20.6) | 320 (20.0) | ||
| Estimated 10-year survival (Charlson Index; mean, SD) | 27.37 (34.69) | 23.32 (33.36) | 25.54 (34.15) | 0.018 |
Frequencies, proportions, means and SDs are displayed. χ2 Test (for 2 × N tables) and t-test (for continuous variables) were performed to compare across the presence of DRP. Missing information: lack of data regarding chronic treatment in clinical records. BMI body mass index, CI confidence interval, DRP drug related problem, HA hospital admissions, NCC number of chronic conditions, NH nursing home, SD standard deviation.