Table 2.
Description of the drug related problems, associated pharmaceutical interventions and outcomes.
| Problems | Causes | Interventions at the prescriber level | Interventions at the drug level | Outcome of intervention | |||||
|---|---|---|---|---|---|---|---|---|---|
| Category | n (%) | Category | n (%) | Category | n (%) | Category | n (%) | Category | n (%) |
| Toxic drug event | 292 (24.64) | Indication for drug-treatment not noticed | 255 (21.52) | Intervention proposed, approved by Prescriber | 788 (66.50) | Dosage changed | 434 (36.62) | Problem totally solved | 878 (74.09) |
| Untreated indication | 273 (23.04) | Pharmacokinetic problem requiring dose adjustment | 205 (17.30) | Intervention proposed, outcome unknown | 165 (13.92) | No intervention (no change) | 356 (30.04) | Outcome intervention not known | 186 (15.70) |
| Effect of drug treatment not optimal | 217 (18.31) | Drug dose too high | 158 (13.33) | Prescriber informed only | 69 (5.82) | New drug started | 147 (12.41) | Problem partially solved | 57 (4.81) |
| Adverse drug event (non-allergic) | 144 (12.15) | Drug dose too low | 102 (8.61) | Intervention proposed, not approved by Prescriber | 69 (5.82) | Drug stopped | 109 (9.20) | No need or possibility to solve the problem | 25 (2.11) |
| No effect of drug treatment/therapy failure | 80 (6.80) | Inappropriate drug (incl. contra-indicated) | 66 (5.57) | No Intervention | 53 (4.47) | Drug changed | 62 (5.23) | Problem not solved, lack of cooperation of prescriber | 23 (1.94) |
Only the five categories most frequently found are listed. Total number of DRP: 1185.