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. 2021 Jan 1;18(4):1030–1038. doi: 10.7150/ijms.47360

Figure 2.

Figure 2

LPS negatively regulates FRA1-mediated glucose metabolism in cervical cancer cells: (A) Glucose content in extracellular medium of Caski-FRA1/Caski-empty vector and Hela-FRA1/Hela-empty vector cells after LPS (50ug/ml). (B) (a) Western blotting analysis of GLUT1, LDHA, SCO2 and COX2 protein levels in Caski-FRA1/Caski-empty vector and Hela-FRA1/Hela-empty vector cells after LPS (50ug/ml). (b-e) Represent relative expression levels of GLUT1, LDHA, SCO2, COX2. (C) Lactic acid production of Caski-FRA1/Caski-empty vector and Hela-FRA1/Hela-empty vector cells after LPS (50ug/ml). (D) Intracellular ATP of Caski-FRA1/Caski-empty vector and Hela-FRA1/Hela-empty vector cells after LPS (50ug/ml). *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001.