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The effects of CSR on MMPs, ADAMTS mRNA expressions in IL-1β-stimulated chondrocytes. (A) Cytotoxicity of CSR was determined by MTT assay. The level of mRNA expression of (B) MMP-1, (C) MMP-3, (D) MMP-9, (E) MMP-13, (F) ADAMTS4 and (G) ADAMTS5 was examined by real-time PCR. ###p < 0.001, ##p < 0.01 compared with normal and ***p < 0.001, **p < 0.01, *p < 0.05 compared with the control group.
