Table 7. Diagnostic performance of C-11 choline PET/CT.
| Author/Year | Purpose | Study/N | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | ACC (%) |
|---|---|---|---|---|---|---|---|
| Ceci/2015 | Staging | Ret/59 | 59 | 90 | 84 | 81 | 71 |
| de Jong/2002 | LN | Pro/18 | 67 | 100 | NR | NR | 94 |
| Picchio/2006 | LN* | NR/27 | 62 | 100 | NR | NR | 89 |
| Brunocilla/2014 | LN** | Ret/26 | 42 | 84 | NR | NR | NR |
| Maurer/2012 | LN | Pro/44 | 58 | 66 | 39 | 81 | 64 |
| Graziani/2015 | LN*** | Ret/25 | 67 | 85 | 80 | 73 | 76 |
| DIS*** | Ret/25 | 90 | 93 | 90 | 93 | 92 |
*, study was done after cystectomy; **, patient-based diagnostic performance was calculated; ***, restaging. N, enrolled patients; PPV, positive predictive value; NPV, negative predictive value; ACC, accuracy; Pro, prospective; Ret, retrospective; LN, lymph node evaluation; DIS, distant lesion evaluation; NR, not reported in the article.