Table 1. GO analysis of DEGs in KIRC.
| Category | Term | Count | % | P value |
|---|---|---|---|---|
| GOTERM_BP | GO:0050900 leukocyte migration | 90 | 10.6 | 7.3e–30 |
| GOTERM_BP | GO:0043062 extracellular structure organization | 76 | 8.9 | 2.9e–25 |
| GOTERM_BP | GO:0030198 ECM organization | 68 | 8.0 | 2.3e–23 |
| GOTERM_BP | GO:0042119 neutrophil activation | 77 | 9.0 | 2.5e–21 |
| GOTERM_BP | GO:0043312 neutrophil degranulation | 75 | 8.8 | 8.5e–21 |
| GOTERM_CC | GO:0062023 collagen-containing ECM | 72 | 8.2 | 2.5e–24 |
| GOTERM_CC | GO:0005788 endoplasmic reticulum lumen | 54 | 6.2 | 3.2e–18 |
| GOTERM_CC | GO:0042611 MHC protein complex | 17 | 1.9 | 6.4e–18 |
| GOTERM_CC | GO:0030667 secretory granule membrane | 52 | 6.0 | 1.5e–17 |
| GOTERM_CC | GO:0009897 external side of plasma membrane | 59 | 6.8 | 1.4e–16 |
| GOTERM_MF | GO:0042605 peptide antigen binding | 15 | 1.8 | 2.1e–12 |
| GOTERM_MF | GO:0005539 glycosaminoglycan binding | 39 | 4.6 | 4.4e–12 |
| GOTERM_MF | GO:0005201 ECM structural constituent | 32 | 3.8 | 7.8e–12 |
| GOTERM_MF | GO:0031406 carboxylic acid binding | 33 | 3.9 | 1.8e–10 |
| GOTERM_MF | GO:0030246 carbohydrate binding | 40 | 4.7 | 2.2e–10 |
The most significantly enriched GO terms are displayed. GO, Gene Ontology; DEGs, differentially expressed genes; KIRC, kidney renal clear cell carcinoma; BP, biological process; CC, cellular component; MF, molecular function; ECM, extracellular matrix.