Table 3. Univariate Cox and multivariate Cox independent prognostic analyses.

Gene	Univariate analysis					Multivariate analysis
	HR	HR-95L	HR-95H	P value		HR	HR-95L	HR-95H	P value
C3	1.20	1.04	1.39	0.01		1.09	0.93	1.27	0.29
C3AR1	0.83	0.71	0.98	0.03		0.80	0.69	0.94	<0.01
HLA-DRA	0.73	0.63	0.85	<0.01		0.73	0.63	0.86	<0.01
HLA-E	0.55	0.42	0.72	<0.01		0.54	0.41	0.72	<0.01

The univariate analysis shows the prognosis value of these four potential biomarkers and the multivariate analysis is used to identify the independent prognostic factors. HR, hazard ratio; HR-95L, hazard ratio 95% confidence intervals lower; HR-95H, hazard ratio 95% confidence intervals upper.