Table 1. Ideal selection criteria for trimodal therapy.

Ideal TMT patient*	Non-ideal TMT patient (high-risk features)*
cT2	cT3-cT4a disease
Complete TURBT	Inability to perform complete TURBT
No hydronephrosis	Presence of hydronephrosis
No CIS	Presence of extensive CIS
Unifocal tumor	Diffuse and multifocal disease
Good bladder function and capacity

*, to be considered an ideal TMT, all characteristics need to be present and no high-risk features. TMT, trimodal therapy; TURBT, transurethral resection of bladder tumor; CIS, carcinoma-in-situ.