Table 4.
Differentially expressed genes encoding KstDs and KshA/B
| Locus_tag | Ortholog in Mtb | Localization | Product | q-value Phyt/Ca | Phyt/C | q-value AcC/Cb | AcC/C |
|---|---|---|---|---|---|---|---|
| KR76_14170 | kshA | Cluster А | 3-ketosteroid-9α-hydroxylase | 2.24E-55 | 10.9 | 1 | 1.3 |
| KR76_27070 | kshA | Cluster D | 3-ketosteroid-9α-hydroxylase | 3.15E-59 | 14.4 | 1 | 1 |
| KR76_14160 | kshB | Cluster А | 3-ketosteroid-9α-hydroxylase | 0.7 | 1.9 | 1 | 1.2 |
| KR76_27080 | kshB | Cluster D | 3-ketosteroid-9α-hydroxylase | 1 | 3.7 | 1 | 1 |
| KR76_02655 | kstD1 | Out of clusters | 3-ketosteroid-Δ1-dehydrogenase | 1.01E-07 | 5.2 | 1 | 1.4 |
| KR76_27115 | kstD1 | Cluster D | 3-ketosteroid-Δ1-dehydrogenase | 1.4E-131 | 16.7 | 1 | 1.2 |
| KR76_27125 | kstD2 | Cluster D | 3-ketosteroid-Δ1-dehydrogenase | 1.44E-14 | 6.4 | 0 | 1207.7 |
| KR76_01140 | kstD3 | Out of clusters | 3-ketosteroid-Δ1-dehydrogenase | 1 | 0.3 | 1 | 0.3 |
| KR76_14500 | kstD3 | Cluster А | 3-ketosteroid-Δ1-dehydrogenase | 1.12E-12 | 6.7 | 1 | 1 |
aPhyt/C – expression changes on Phytosterol with respect to control
bAcC/C – expression changes on AcC with respect to control