Fig. 1.

Schematic of the image workflow for applying the trained generator on a new 2D transverse slice of the CBCT of a breast cancer patient to create a sCT. After image acquisition, registration (1) and pre-processing (2) the trained network is deployed producing converted CBCT (${\mathrm{CBCT}}_{\mathrm{conv}}$, 3) which substituted the original CT within ${\mathrm{Mask}}_{\mathrm{CBCT}}$ obtaining the so-called synthetic CT (sCT).