Supplementary figure 2.

Sample dose distributions of the pre-treatment plan and adapted plans using methods A – F for the case in which it was not possible to satisfy clinical dose criteria. Anatomical contours are shown for the PTV (red), bowel (green) and sigmoid (blue). Method A – F describe: A the original segments, B adapt segments, C optimize weights from segments, D optimize weights from fluence, E optimize weights and shapes from segments and F optimize weights and shapes from fluence, respectively.