Fig. 5.

The effect of luteolin on LPS/TLR4/NF-κB pathway. a The TNF-α and IL-8 level in cultural supernatants of EA.hy926 cells. The data were expressed as means ± SEM (n = 8). Significant differences were indicated by ^##P< 0.01 as compared with control group, ^**P< 0.01 as compared with LPS group. b The expression of TLR4, Myd88, IκB-α, NF-κB/p65, ICAM-1 and VCAM-1, and activation of IκB-α and NF-κB/p65 in EA.hy926 cells