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Comparison of cancer driver variant predictors on the DRGN benchmark data sets. The last column shows the AUC drop with respect the EXPDRV+ALL data set in Table 2
| Method | AUC | AUPRC | AUC drop |
|---|---|---|---|
| ParsSNP | 59.4 | 52.0 | 27.5 |
| CanDrA v+ | 66.2 | 64.7 | 20.9 |
| Chasm 3.1 | 76.6 | 74.1 | 14.5 |
| CHASMplus | 72.3 | 69.8 | 22.0 |
| FATHMM | 69.1 | 65.9 | 21.9 |
| TransFIC | 59.6 | 53.0 | 8.4 |
| Condel | 55.9 | 51.7 | 8.4 |
| DEOGEN2 | 57.2 | 48.7 | 11.6 |
| CADD | 63.6 | 55.5 | 10.1 |
| M-CAP | 47.4 | 45.9 | 6.6 |
| MetaSVM | 55.7 | 49.2 | 11.1 |
| Dummy | 50.0 | 44.2 | 48.1 |
