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. 2020 Dec 31;6(1):301–316. doi: 10.1021/acsomega.0c04595

Table 2. Anticancer Screenings of the Synthesized Compounds against Caco-2, HCT116, HeLa, and MCF7 Human Cancer Cell Linesa.

compound no Caco-2 HCT-116 HeLa MCF-7
7 165.33 ± 2.45 >200 124.67 ± 4.67 93.43 ± 3.56
8 168.71 ± 1.98 >200 120.98 ± 4.84 98.26 ± 4.41
16 79.67 ± 1.67 91.19 ± 4.23 39.75 ± 2.14 34.79 ± 1.73
17 16.36 ± 1.12 43.45 ± 2.34 4.41 ± 0.23 0.31 ± 0.01
18 19.09 ± 1.02 55.60 ± 2.78 24.65 ± 1.87 17.29 ± 1.13
19 85.72 ± 2.12 97.23 ± 3.45 42.17 ± 2.46 36.06 ± 2.05
20 96.79 ± 3.18 124.32 ± 4.45 56.35 ± 3.78 52.75 ± 3.46
21 99.47 ± 3.15 126.87 ± 4.67 61.10 ± 3.90 54.68 ± 3.57
22 4.98 ± 0.15 19.89 ± 0.63 7.47 ± 0.39 3.31 ± 0.03
23 12.34 ± 1.41 35.78 ± 1.98 29.25 ± 1.23 23.09 ± 1.84
24 10.21 ± 0.38 30.09 ± 1.65 19.05 ± 0.45 14.78 ± 1.23
25 7.22 ± 0.26 22.34 ± 0.87 11.05 ± 0.56 4.46 ± 0.02
26 14.18 ± 1.51 39.55 ± 2.11 31.79 ± 2.04 28.46 ± 1.93
27 11.67 ± 1.34 32.41 ± 1.92 22.08 ± 1.29 18.14 ± 1.14
doxorubicin 5.17 ± 0.25 5.64 ± 0.17 1.25 ± 0.02 0.65 ± 0.01
a

IC50 values are expressed as mean ± SD of three independent experiments.