Table 2. Anticancer Screenings of the Synthesized Compounds against Caco-2, HCT116, HeLa, and MCF7 Human Cancer Cell Linesa.
compound no | Caco-2 | HCT-116 | HeLa | MCF-7 |
---|---|---|---|---|
7 | 165.33 ± 2.45 | >200 | 124.67 ± 4.67 | 93.43 ± 3.56 |
8 | 168.71 ± 1.98 | >200 | 120.98 ± 4.84 | 98.26 ± 4.41 |
16 | 79.67 ± 1.67 | 91.19 ± 4.23 | 39.75 ± 2.14 | 34.79 ± 1.73 |
17 | 16.36 ± 1.12 | 43.45 ± 2.34 | 4.41 ± 0.23 | 0.31 ± 0.01 |
18 | 19.09 ± 1.02 | 55.60 ± 2.78 | 24.65 ± 1.87 | 17.29 ± 1.13 |
19 | 85.72 ± 2.12 | 97.23 ± 3.45 | 42.17 ± 2.46 | 36.06 ± 2.05 |
20 | 96.79 ± 3.18 | 124.32 ± 4.45 | 56.35 ± 3.78 | 52.75 ± 3.46 |
21 | 99.47 ± 3.15 | 126.87 ± 4.67 | 61.10 ± 3.90 | 54.68 ± 3.57 |
22 | 4.98 ± 0.15 | 19.89 ± 0.63 | 7.47 ± 0.39 | 3.31 ± 0.03 |
23 | 12.34 ± 1.41 | 35.78 ± 1.98 | 29.25 ± 1.23 | 23.09 ± 1.84 |
24 | 10.21 ± 0.38 | 30.09 ± 1.65 | 19.05 ± 0.45 | 14.78 ± 1.23 |
25 | 7.22 ± 0.26 | 22.34 ± 0.87 | 11.05 ± 0.56 | 4.46 ± 0.02 |
26 | 14.18 ± 1.51 | 39.55 ± 2.11 | 31.79 ± 2.04 | 28.46 ± 1.93 |
27 | 11.67 ± 1.34 | 32.41 ± 1.92 | 22.08 ± 1.29 | 18.14 ± 1.14 |
doxorubicin | 5.17 ± 0.25 | 5.64 ± 0.17 | 1.25 ± 0.02 | 0.65 ± 0.01 |
IC50 values are expressed as mean ± SD of three independent experiments.