Table 2.

Comparisons of signs and symptoms of Lassa fever survivors, febrile and matched controls.

Signs and symptoms	Lassa (n = 47) n, (%)	Fever (n = 29) n, (%)	Control (n = 71) n, (%)	Overall p-valuea,b	p-valuea,c	p-valuea,d
Weight loss	27 (57)	10 (34)	34 (48)	0.146	0.052	0.309
Paresthesia	11 (23)	5 (17)	13 (18)	0.733	0.522	0.501
Difficulty with balance/walking	26 (55)	11 (38)	14 (20)	<0.001	0.141	<0.001
Tremor	20 (43)	9 (31)	17 (24)	0.105	0.315	0.033
Lymphadenopathy	9 (19)	2 (7)	5 (7)	0.104	0.140	0.046
Headache	35 (74)	16 (55)	47 (66)	0.223	0.082	0.339
Hair loss	15 (32)	4 (14)	5 (7)	0.002	0.076	<0.001
Lightheadedness	25 (53)	13 (45)	21 (30)	0.018	0.479	0.010
Fainting	2 (4)	2 (7)	5 (7)	0.800	0.616	0.530
Vertigo	10 (21)	8 (28)	9 (13)	0.212	0.530	0.213
Seizures	1 (2)	2 (7)	3 (4)	0.593	0.300	0.538
Hallucinations	8 (17)	5 (17)	9 (13)	0.735	0.980	0.510
Hearing loss	8 (17)	2 (7)	1 (1)	0.005	0.205	0.002
Tinnitus	13 (28)	10 (34)	15 (21)	0.369	0.529	0.414
Blurred vision	9 (19)	6 (21)	9 (13)	0.505	0.870	0.338
Difficulty speaking	9 (19)	6 (21)	1 (1)	<0.001	0.870	<0.001
Difficulty thinking clearly	6 (13)	1 (3)	5 (7)	0.319	0.172	0.295
Difficulty swallowing	8 (17)	3 (10)	12 (17)	0.658	0.422	0.986
Change in the taste of food	18 (38)	10 (34)	12 (17)	0.020	0.738	0.008
Change in smell	7 (15)	6 (21)	7 (10)	0.355	0.514	0.902
Hospitalized since illness	5 (11)	8 (28)	5 (7)	0.028	0.057	0.492

^aα level required for significance adjusted through Bonferroni correction to 0.0023.

^bOverall p-value of logistic regression model using asymptotic Chi-squared test.

^cPearson’s Chi-squared test comparing Lassa fever survivors and febrile controls

^dPearson’s Chi-squared test comparing Lassa fever survivors and matched controls