Table 1.
Geometric, setup and treatment characteristics of the seven patients treated with EMT real-time tracking.
| P1 | P2 | P3 | P4 | P5 | P6 | P7 | |
|---|---|---|---|---|---|---|---|
| Tumor location | Apical segment of upper left lobe | Lingular segment of upper left lobe | Apical segment of lower left lobe | Overlapping anterior segment of upper left lobe and superior segment lower left lobe | Lower right lobe | Upper right lobe | Upper left lobe |
| PTV volume (cm3) | 11.5 | 9.1 | 24.7 | 77.4 | 11.5 | 7.1 | 13.2 |
| Treatment modality | FB | DIBH | FB | FB | DIBH | DIBH | DIBH |
| Days between EMT implantation and simulation CT | 15 | 9 | 32 | 8 | 7 | 7 | 41 |
| Days between simulation CT and 1st treatment | 7 | 11 | 15 | 13 | 28 | 14 | 21 |
| Prescribed dose | 8 × 7.5 Gy | 8 × 7.5 Gy | 5 × 12 Gy | 8 × 7.5 Gy | 3 × 20 Gy | 3 × 20 Gy | 5 × 12 Gy |
| Overall treatment time (days) | 17 | 19 | 10 | 21 | 7 | 8 | 14 |
| Tumor-EMT centroid distance (mm) | 4 | 13 | 18 | 10 | 11 | 15 | 17 |
| Inter-EMTs distances on planning CT (mm) | 12 | 39/45/38 | 9/60/57 | 49/54/58 | 31/26/20 | 46/46/37 | 33/32/61 |
| GTV centroid motion amplitude on 4DCT (LR/SI/AP) (mm) | <1/<1/<1 | 2/4/3 | 2/6/2 | 1/4/2 | 2/8/4 | 1/4/6 | 2/2/2 |
| Median setup time [range] (min) | 8.0 [4.6–9.9] | 11.0 [9.3–18.1] | 10.5 [5.3–14.6] | 8.7 [4.9–34.1] | 10.5 [9.4–13.0] | 19.5 [8.6–22.4] | 13.1 [11.5–13.5] |
| Median inter-EMTs distance differences [range] (mm) | 0.1 [0.0–0.2] | 1.4 [0.0–3.7] | 1.7 [0.7–4.3] | 1.8 [1.3–3.3] | 0.6 [0.3–1.4] | 2.7 [0.6–4.5] | 1.0 [0.1–1.9] |
| Median geometrical residual [range] (mm) | 0.1 [0.0–0.1] | 0.9 [0.6–1.7] | 1.3 [0.8–2.0] | 1.3 [0.8–1.7] | 0.4 [0.4–0.6] | 1.9 [1.7–2.0] | 0.8 [0.7–1.0] |
| Median session time [range] (min) | 10.3 [7.3–12.0] | 17.1 [12.4–30.0] | 16.4 [10.0–20.3] | 15.3 [7.6–36.5] | 13.0 [12.8–28.1] | 33.5 [25.5–39.3] | 22.1 [21.5–23.4] |
| Median number of beam holds per fraction [range] | 0 [0–1] | 4.5 [0–14] | 20.5 [2–36] | 2 [0–29] | 12 [9–18] | 6 [5–11] | 6 [4–8] |
Abbreviations: PTV: planning target volume, EMT: electromagnetic transponder, FB: free-breathing, DIBH: deep inspiration breath-hold, LR: left–right, SI: supero-inferior, AP: antero-posterior, P#: patient #.