Table 1.
Maternal-to-fetal transfer of drugs commonly used during GA. ∗Crosses to a limited extent (not clinically significant).
| Drug class | Examples | Crosses uteroplacental barrier? |
|---|---|---|
| Intravenous agents | Thiopental, propofol, ketamine | Yes |
| Inhalational agents | Isoflurane, sevoflurane, desflurane | Yes |
| Benzodiazepines | Midazolam, lorazepam | Yes |
| Opioids | Morphine, fentanyl, remifentanil | Yes |
| NMBAs | Vecuronium, rocuronium, suxamethonium | No |
| NMBA reversal agents | Neostigmine | Yes∗ |
| Sugammadex | Yes∗ | |
| Anticholinergic agents | Atropine | Yes |
| glycopyrrolate | Yes∗ |