Longitudinal changes in neutrophils.
(A) Boxplot of neutrophil count according to worst outcome in the entire cohort measured at day 0. Discharge, discharged within 24 hours; Inpt for non-COVID-19 reason, inpatient due to reason other than COVID-19 and outcome not altered by infection; COVID-19 no O2, admitted due to COVID-19 infection but did not require oxygen; admitted plus O2, admitted due to COVID-19 and required oxygen; admitted plus ICU, admitted due to COVID-19 and required intensive care; COVID-19 death, death due to other. (B) Boxplot of neutrophil count grouped by oxygen requirement in the entire cohort measured at day 0. (C) Boxplot of neutrophil count grouped by death in the entire cohort measured at day 0. (D) Boxplot of whether the given G-CSF grouped by oxygen requirement in the Manchester cohort measured at day 0. (E) Boxplot of whether the given G-CSF grouped by death in the Manchester cohort measured at day 0. COVID-19, coronavirus disease 2019; G-CSF, granulocyte colony-stimulating factor; ICU, intensive care unit.