Table 2. Linearity, Range, and LLOQ of Artemisinin, Deoxyartemisinin, and 10-Deoxoartemisinin in Rat Plasma Determined by the LC–MS/MS Technique.
compound | calibration equation | correlation coefficient (R) | range (ng/mL) | LLOQ (ng/mL) |
---|---|---|---|---|
artemisinin | y = 2.65 × 10–5x – 7.19 × 10–6 | 0.9961 | 1.00–1000 | 1.00 |
deoxyartemisinin | y = 6.80 × 10–3x – 6.45 × 10–4 | 0.9968 | 1.00–1000 | 1.00 |
10-deoxoartemisinin | y = 2.32 × 10–4x + 7.79 × 10–5 | 0.9951 | 1.00–1000 | 1.00 |